Paramilitary units armed with batons and riot shields have been smashing up stalls of street traders as they target the huge informal sector.
The black market has thrived as jobless Zimbabweans struggle to make a living.
The police chief said informal business operators had been fined for operating without licences or possessing scarce staple items such as maize meal, sugar and petrol intended for resale on the black market.
Police have destroyed 34 flea markets and netted some Z$900m ($100,000) in fines and seized some Z$2.2bn of goods.
Zimbabweans in Harare are said to be absolutely furious at the police operation.